Issue N# 2 - 2007
CERVICO-FACIAL PATHOLOGY
Kikuchi-Fujimoto’s disease: 3 cases report
Authors : Khalifa M, Kaabia N, Gannouchi N, Sriha B, Bahri F, Letaief O. A. (Sousse)
Ref. : Rev Laryngol Otol Rhinol. 2007;128,2:117-119.
Article published in french 
Downloadable PDF document french
Summary :
Objective: Kikuchi-Fujimoto’s is a rare disease, characterized by the diversity of clinical symptoms, with predominance of enlarged cervical lymph nodes and fever. We report three cases with different presentations. Material and method: The first one was a classic form, frequently described in literature. The second was characterized by concomitant association with systemic lupus erythematosus. Histologic findings of Kikuchi’s disease were the presence of nuclear debris, absence of haemathoxilin bodies and neutrophils polynuclears. The presentation of the third case was acute meningitis with cervical lymphadenopathy. Lumber puncture showed lymphocytic meningitis, mild hypoglycorrhachia and hyperproteinrrhachia. Favourable evolution was noted in all cases without recurrence. Conclusion: Wathever its presentation the prognosis of the Kikuchi-Fujimoto’s disease is generally benign with a spontaneously favorable evolution between 1 to 6 months.
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