Issue N# 4 - 2000
RHINOLOGY
Esthesioneuroblastoma.
Authors : J. Martel, V. Darrouzet, J. Y. Duclos, J. P. Bébéar, D. Stoll (Bordeaux)
Ref. : Rev Laryngol Otol Rhinol. 2000;121,4:227-236.
Article published in french 
Downloadable PDF document french
Summary :
Olfactory neuroblastomas are rare malignant tumours of the nose arising from the olfactory epithelium. In a retrospective series of 18 cases and a review of the literature, the authors establish the main features of this tumour. They emphasise the difficulties of histological examination, often requiring immuno-cyt-chemistery and electron microscopy. They point out the value of a new classification, and confirm treatments being radio-surgical, with use of the combined rhino-neurosurgical approach when there is extension to the cribriform plate. They report a 5-year survival of 91.5%, with 87.5% at 10 years. The high incidence of lymph gland metastases (16.6%) is greater than that of local recurrence (11%) especially in the more advanced cases. The question of prophylactic treatment of the neck nodes is one to be considered.
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